To ensure their survival in natural habitats, plants must recognize and respond to a wide variety of insect herbivores. Aphids and other Hemiptera pose a particular challenge, because they cause relatively little direct tissue damage when inserting their slender stylets intercellularly to feed from the phloem sieve elements. Plant responses to this unusual feeding strategy almost certainly include recognition of aphid salivary components and the induction of phloem‐specific defenses. Due to the excellent genetic and genomic resources that are available for (...) Arabidopsis thaliana (Arabidopsis), this plant was chosen as a model system to study the metabolic and transcriptional responses to infestation by two aphids, Myzus persicae (green peach aphid, a broad generalist) and Brevicoryne brassicae (cabbage aphid, a crucifer‐feeding specialist). Future research on Arabidopsis–aphid interactions will lead to the identification of aphid‐specific elicitors, components of the defense‐signaling pathway, and additional metabolic responses that are induced by aphid infestation. BioEssays 29:871–883, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

Byun et al. describe how deaf signers deal with communication problems in first encounters with signers of different languages. They show that the basic Conversation Analytic repair mechanisms for dealing with verbal troubles are largely reproduced in gesture and sign, including details of turn‐taking structure, timing and form. This underlines the role of repair as a basic resource for linguistic and interactional creativity across modalities.

Byun et al. describe how deaf signers deal with communication problems in first encounters with signers of different languages. They show that the basic Conversation Analytic repair mechanisms for dealing with verbal troubles are largely reproduced in gesture and sign, including details of turn‐taking structure, timing and form. This underlines the role of repair as a basic resource for linguistic and interactional creativity across modalities.

InhaltVorwortSiglenverzeichnisDaniel BREAZEALE: »Der Blitz der Einsicht« and »der Akt der Evidenz«. A Theme from Fichte’s Berlin Introductions to PhilosophyJürgen STAHL: Von der Form der Anschauung zur Anschauung der Form. Zu Fichtes Verständnis des Formbegriffs Albert MUES: Die Position der Anschauung im Wissen oder Die Position der Anschauung in der Welt. Der Unsinn der SubjektphilosophieChristoph ASMUTH: Transzendentalphilosophie oder absolute Metaphysik? Grundsätzliche Fragen an Fichtes SpätphilosophieMarek J. SIEMEK: Unendlichkeit und Schranke. Zum Fichteschen Entwurf einer transzendentalen Ontologie des WissensTom ROCKMORE: On Fichte and (...) IdealismSabine AMMON: Realismus oder Idealismus? – Irrealismus!Akira OMINE: Der Begriff des Übersinnlichen in der Philosophie FichtesRoderich BARTH: Wahrheit als Sein von Einheit. Die gewißheitstheoretische Reformulierung des absoluten Wahrheitsbegriffs in Fichtes Phänomenologie von 1804-IIArkadij LUKJANOW: Auf der Suche nach einer neuen Theorie des Absoluten. Die Idee der Synthesis in den späteren Systemen von Fichte und Schelling«Lu De VOS: Der Gedanke des Lebens in den späten Schriften FichtesMichael GERTEN: Geistige Blindheit und der Sinn für Philosophie. Das systematische Problem einer Einleitung in Fichtes WissenschaftslehreKai GREGOR: »Revolution der Gesinnung« und »Vollendung der Freiheit« – Wesen und Möglichkeit höherer Lebensformen bei Kant und FichteVioletta L. WAIBEL: Die bildende Kraft des Wissens vom Wissen in der Spätphilosophie Johann Gottlieb Fichtes Elvira GAREEWA: Wissen als ein freies und selbständiges Leben in den »Thatsachen des Bewußtseyns« Franco GILLI: Die Präsenz der ›Populärphilosophie‹ im Spätwerk FichtesHans Georg von MANZ: Die Funktion der »Tatsachen des Bewußtseins« im Blick auf die Wissenschaftslehre George di GIOVANNI: Sacramentalizing the World: On Fichte’s Wissenschaftslehre of 1810Stamatios D. GEROGIORGAKIS: Der Begriff Schema in Fichtes Spätwerk. Seine Unterschiede zum Schemabegriff in Fichtes Frühwerk und seine Einbettung in der philosophischen Tradition vor KantJacinto Rivera de ROSALES: Die transzendentale Logik . Ihr systematischer Ort und ihre BedeutungAlessandro BERTINETTO: Die transzendentale Argumentation in der Transzendentalen Logik FichtesMarc MAESSCHALCK: Attention et réflexivité dans la Logique de 1812 et la dernière philosophie de Fichte. (shrink)

Computer science advocates institutional frameworks as an effective tool for modelling policies and reasoning about their interplay. In practice, the rules or policies, of which the institutional framework consists, are often specified using a formal language, which allows for the full verification and validation of the framework (e.g. the consistency of policies) and the interplay between the policies and actors (e.g. violations). However, when modelling large-scale realistic systems, with numerous decision-making entities, scalability and complexity issues arise making it possible only (...) to verify certain portions of the problem without reducing the scale. In the social sciences, agent-based modelling is a popular tool for analysing how entities interact within a system and react to the system properties. Agent-based modelling allows the specification of complex decision-making entities and experimentation with large numbers of different parameter sets for these entities in order to explore their effects on overall system performance. In this paper we describe how to achieve the best of both worlds, namely verification of a formal specification combined with the testing of large-scale systems with numerous different actor configurations. Hence, we offer an approach that allows for reasoning about policies, policy making and their consequences on a more comprehensive level than has been possible to date. We present the institutional agent-based model methodology to combine institutional frameworks with agent-based simulations). We furthermore present J-InstAL, a prototypical implementation of this methodology using the InstAL institutional framework whose specifications can be translated into a computational model under the answer set semantics, and an agent-based simulation based on the jason tool. Using a simplified contract enforcement example, we demonstrate the functionalities of this prototype and show how it can help to assess an appropriate fine level in case of contract violations. (shrink)

The knower paradox states that the statement ‘We know that this statement is false’ leads to inconsistency. This article presents a fresh look at this paradox and some well-known solutions from the literature. Paul Égré discusses three possible solutions that modal provability logic provides for the paradox by surveying and comparing three different provability interpretations of modality, originally described by Skyrms, Anderson, and Solovay. In this article, some background is explained to clarify Égré’s solutions, all three of which hinge on (...) intricacies of provability logic and its arithmetical interpretations. To check whether Égré’s solutions are satisfactory, we use the criteria for solutions to paradoxes defined by Susan Haack and we propose some refinements of them. This article aims to describe to what extent the knower paradox can be solved using provability logic and to what extent the solutions proposed in the literature satisfy Haack’s criteria. Finally, the article offers some reflections on the relation between knowledge, proof, and provability, as inspired by the knower paradox and its solutions. (shrink)

Research has shown the importance of engaging in networking behaviors for employees’ career success. Networking behaviors can be seen as a proactive way of creating access to career-related social resources and we argue that this type of proactive career behaviors might be particularly relevant for freelancers who cannot depend on an organizational career system supporting their further development, yet whose careers are characterized by high levels of uncertainty and unpredictability. To date, however, our understanding of how freelancers, being a category (...) of workers that are deprived of an organizational context of support for career development, can safeguard their employability, is limited. Therefore, this study addresses this gap and investigates whether freelancers’ networking behaviors are positively associated with career outcomes, through the mediating role of the need for relatedness fulfillment and employability-enhancing competencies. Hypotheses are tested via Structural Equation Modelling using a sample of 1,874 freelancers from Belgium, France, Germany, the Netherlands and the United Kingdom. The results generally support our hypotheses, providing evidence for a significant association between networking behaviors and need for relatedness fulfillment, and between networking behaviors and employability-enhancing competencies. Moreover, we found a significant association between need for relatedness fulfillment and employability-enhancing competencies, being the mediators in our research model and the outcomes of career satisfaction and future career opportunities. Implications for career development in the contemporary workplace are discussed, with particular attention for need for relatedness fulfillment, employability, and sustainable careers of freelance workers. (shrink)

Der ärztliche Umgang mit Opiaten und Sedativa bei Patienten am Lebensende kann ethische Fragen aufwerfen. Entsprechende Entscheidungen blieben bisher in aller Regel der ärztlichen Berufskunst und -pflicht überantwortet. Heute aber gerät dieser Bereich zunehmend auch in den Blickwinkel des Rechts. Ausdruck davon sind Bestrebungen, die indirekte Sterbehilfe, allenfalls auch die terminale Sedierung gesetzlich zu regeln. Ausgehend von einer Ist-Analyse der ärztlichen Praxis sowie von bereits bestehenden Regulierungen untersucht diese Arbeit die Konsequenzen derartiger Bestrebungen. Es zeigt sich, dass der Versuch, die (...) Thematik der indirekten Sterbehilfe für sich allein, also unter Vermeidung einer Regelung der direkt aktiven Sterbehilfe, zu behandeln, zu großen Schwierigkeiten führen würde. Ernüchternd sind aber auch die Erfahrungen aus den Niederlanden, derartige Fragen im Rahmen eines umfassenden Sterbehilfegesetzes anzugehen. Insgesamt ist somit zu befürchten, dass der Versuch einer detaillierten gesetzlichen Regelung dieses Bereiches mehr neue Grauzonen und Unsicherheiten schafft, als er zu beseitigen vermag. (shrink)

Background In the ethical and clinical literature, cases of parents who want treatment for their child to be withdrawn against the views of the medical team have not received much attention. Yet resolution of such conflicts demands much effort of both the medical team and parents. Objective To discuss who can best protect a child9s interests, which often becomes a central issue, putting considerable pressure on mutual trust and partnership. Methods We describe the case of a 3-year-old boy with acquired (...) brain damage due to autoimmune-mediated encephalitis whose parents wanted to stop treatment. By comparing this case with relevant literature, we systematically explored the pros and cons of sharing end-of-life decisions with parents in cases where treatment is considered futile by parents and not (yet) by physicians. Conclusions Sharing end-of-life decisions with parents is a more important duty for physicians than protecting parents from guilt or doubt. Moreover, a request from parents on behalf of their child to discontinue treatment is, and should be, hard to over-rule in cases with significant prognostic uncertainty and/or in cases with divergent opinions within the medical team. (shrink)

In spoken interactions, interlocutors carefully plan and time their utterances, minimising gaps and overlaps between consecutive turns. Cross-linguistic comparison has indicated that spoken languages vary only minimally in terms of turn-timing, and language acquisition research has shown pre-linguistic vocal turn-taking in the first half year of life. These observations suggest that the turn-taking system may provide a fundamental basis for our linguistic capacities. The question remains however to what extent our capacity for rapid turn-taking is determined by modality constraints. The (...) avoidance of overlapping turns could be motivated by the difficulty of hearing and speaking at the same time. If so, turn-taking in sign might show greater toleration for overlap. Alternatively, signed conversations may show a similar distribution of turn-timing as spoken languages, thus avoiding both gaps and overlaps. To address this question we look at turn-timing in question-answer sequences in spontaneous conversations of Sign Language of the Netherlands. The findings indicate that although there is considerable overlap in two or more signers' articulators in conversation, when proper allowance is made for onset preparation, post-utterance retraction and the intentional holding of signs for response, turn-taking latencies in sign look remarkably like those reported for spoken language. This is consistent with the possibility that, at least with regard to responses to questions, speakers and signers follow similar time courses in planning and producing their utterances in on-going conversation. This suggests that turn-taking systems may well be a shared cognitive infrastructure underlying all modern human languages, both spoken and signed. (shrink)

Resumen Se estudia comparativamente el desempeño de adultos mayores y de adultos jóvenes en una tarea concurrente que consiste en leer oraciones ecuacionales mientras, al mismo tiempo, se retienen en la memoria tres palabras. El propósito del experimento es averiguar si existe un efecto de las variables edad, memoria operativa, complejidad sintáctica e interferencia de una carga concurrente de memoria en el procesamiento y comprensión de oraciones de sintaxis compleja. El análisis estadístico multinivel realizado revela que tanto el procesamiento en (...) línea de las oraciones ecuacionales como su comprensión se ven afectados significativamente por la edad de los participantes cuando opera una carga de memoria concurrente. Las variables memoria operativa y complejidad sintáctica, por su parte, afectan también significativamente el desempeño de los sujetos, pero independientemente de su edad.The performance of older and young adults in a concurrent task -to read equational sentences while at the same time the subjects retain in memory three words- is comparatively studied. The purpose of the experiment is to find out if there is an effect of the variables of age, working memory, syntactic complexity and interference of a concurrent memory load processing on the comprehension of syntactically complex sentences. The multilevel statistical analysis reveals that both online processing of cleft sentences as their understanding is significantly affected by the age of participants when operating a concurrent memory load. The working memory variables and syntactical complexity, meanwhile, also significantly affect the performance of subjects, but regardless of age. (shrink)

Signed utterances are densely packed with pointing signs, reaching a frequency of one in six signs in spontaneous conversations (de Vos, 2012; Johnston, 2013a; Morford & MacFarlane, 2003). These pointing signs attain a wide range of functions and are formally highly diversified. Based on corpus analysis of spontaneous pointing signs in Kata Kolok, a rural signing variety of Bali, this paper argues that the full meaning potentials of pointing signs come about through the integration of a varied set of linguistic (...) and extralinguistic cues. Taking this hybrid nature of pointing phenomena into account, it is argued that pointing signs may become an intrinsic aspect of sign language grammars through two mechanisms: morphemization and syntactic integration. Although not entailed in this research, this approach could implicate that some highly systematized pointing systems of speaking communities may to a degree be grammatical as well. (shrink)

ZusammenfassungDer ärztliche Umgang mit Opiaten und Sedativa bei Patienten am Lebensende kann ethische Fragen aufwerfen. Entsprechende Entscheidungen blieben bisher in aller Regel der ärztlichen Berufskunst und -pflicht überantwortet. Heute aber gerät dieser Bereich zunehmend auch in den Blickwinkel des Rechts. Ausdruck davon sind Bestrebungen, die indirekte Sterbehilfe, allenfalls auch die terminale Sedierung gesetzlich zu regeln. Ausgehend von einer Ist-Analyse der ärztlichen Praxis sowie von bereits bestehenden Regulierungen untersucht diese Arbeit die Konsequenzen derartiger Bestrebungen. Es zeigt sich, dass der Versuch, die (...) Thematik der indirekten Sterbehilfe für sich allein, also unter Vermeidung einer Regelung der direkt aktiven Sterbehilfe, zu behandeln, zu großen Schwierigkeiten führen würde. Ernüchternd sind aber auch die Erfahrungen aus den Niederlanden, derartige Fragen im Rahmen eines umfassenden Sterbehilfegesetzes anzugehen. Insgesamt ist somit zu befürchten, dass der Versuch einer detaillierten gesetzlichen Regelung dieses Bereiches mehr neue Grauzonen und Unsicherheiten schafft, als er zu beseitigen vermag. (shrink)

Los niños con trastorno por déficit de atención con hiperactividad presentan alteraciones en el desarrollo de la función ejecutiva que se traducen en dificultades del control atencional y de la flexibilidad cognitiva. Considerando la complejidad de los procesos involucrados en la comprensión de lectura y el papel fundamental que en ellos cumple la función ejecutiva, puede esperarse que los niños con TDAH presenten diferencias en su desempeño lector en comparación con sus pares sin TDAH. El presente estudio, de carácter correlacional-predictivo, (...) tiene como propósito determinar si tales diferencias de comprensión lectora existen realmente y si es posible predecirlas a partir de la función ejecutiva. Para ello se seleccionaron 71 escolares de tercer y cuarto año de enseñanza básica y se les evaluó la habilidad de comprensión de lectura, el reconocimiento de palabras, la amplitud de la memoria de trabajo verbal, el control atencional y la velocidad de procesamiento. Con el fin de determinar qué variables tenían capacidad para predecir el nivel de comprensión de los escolares se aplicó un análisis de regresión logística binaria. Los resultados ponen en evidencia que el TDAH afecta significativamente el desempeño lector de los escolares y que las variables vinculadas a la función ejecutiva, especialmente la memoria de trabajo, son buenos predictores del rendimiento en comprensión de lectura. (shrink)

A rapidly emerging hegemonic neuro-culture and a booming neural subjectivity signal the entry point for an inquiry into the status of the signifier neuro as a universal passe-partout. The wager of this paper is that the various appropriations of the neurosciences in the media and in academia itself point to something essential, if not structural, in connection with both the discipline of the neurosciences and the current socio-cultural and ideological climate. Starting from the case of neuroeducation, the genealogy of the (...) neurological turn is linked to the history of psychology and its inextricable bond with processes of psychologisation. If the neurological turn risks not merely neglecting the dimension of critique, but also obviating its possibility, then revivifying a psy-critique might be necessary in order to understand today’s neural subjectivity and its place within current biopolitics. (shrink)

Machine Learning (ML) is on the rise in medicine, promising improved diagnostic, therapeutic and prognostic clinical tools. While these technological innovations are bound to transform health care, they also bring new ethical concerns to the forefront. One particularly elusive challenge regards discriminatory algorithmic judgements based on biases inherent in the training data. A common line of reasoning distinguishes between justified differential treatments that mirror true disparities between socially salient groups, and unjustified biases which do not, leading to misdiagnosis and erroneous (...) treatment. In the curation of training data this strategy runs into severe problems though, since distinguishing between the two can be next to impossible. We thus plead for a pragmatist dealing with algorithmic bias in healthcare environments. By recurring to a recent reformulation of William James’s pragmatist understanding of truth, we recommend that, instead of aiming at a supposedly objective truth, outcome-based therapeutic usefulness should serve as the guiding principle for assessing ML applications in medicine. (shrink)

Recent years have seen a rapid growth in neuroscientific research, and an expansion beyond basic research to incorporate elements of the arts, humanities and social sciences. It has been suggested that the neurosciences will bring about major transformations in the understanding of ourselves, our culture and our society. In academia one finds debates within psychology, philosophy and literature about the implications of developments within the neurosciences, and the emerging fields of educational neuroscience, neuro-economics, and neuro-aesthetics also bear witness to a (...) 'neurological turn' which is currently taking place. Neuroscience and Critique is a ground-breaking edited collection which reflects on the impact of neuroscience in contemporary social science and the humanities. It is the first book to consider possibilities for a critique of the theories, practices, and implications of contemporary neuroscience. Bringing together leading scholars from several disciplines, the contributors draw upon a range of perspectives, including cognitive neuroscience, critical philosophy, psychoanalysis, and feminism, and also critically examine several key ideas in contemporary neuroscience, including: The idea of "neural personhood" Theories of emotion in affective neuroscience Empathy, intersubjectivity and the notion of "embodied simulation" The concept of an "emo-rational" actor within neuro-economics. The volume will stimulate further debate in the emerging field of interdisciplinary studies in neuroscience, and will appeal to researchers and advanced students in a range of disciplines including critical psychology, philosophy, and critical studies. (shrink)

Humanitarian aid’s psycho-therapeutic turn in the 1990s was mirrored by the increasing emotionalization and subjectivation of fund-raising campaigns. In order to grasp the depth of this interconnectedness, this article argues that in both cases what we see is the post-Fordist production paradigm at work; namely, as Hardt and Negri put it, the direct production of subjectivity and social relations. To explore this, the therapeutic and mental health approach in humanitarian aid is juxtaposed with the more general phenomenon of psychologization. This (...) allows us to see that the psychologized production of subjectivity has a problematic waste-product as it reduces the human to Homo sacer, to use Giorgi Agamben’s term. Drawing out a double matrix of a de-psychologizing psychologization connected to a politicizing de-politicization, it will further become possible to understand psycho-therapeutic humanitarianism as a case of how, in these times of globalization, psychology, subjectivity and money are all interrelated. (shrink)

The long standing reign of psychology as the privileged partner of education has, arguably, now been superseded by the neurosciences. Given that this helped to drive the emergent field of neuroeducation, it is crucial to ask what changes in education, if anything does in fact change, when the hitherto hegemonic psychologising discourse is substituted for a neurological one. The primary contention of this paper is that with the neuro-turn a process of “neurologisation” has also been initiated, which can be analysed (...) by taking into account its genealogical predecessor, psychologisation. In doing so, I argue, one ultimately discerns a primordial incompatibility between education and neuroscience, one that can be traced back to the fundamental and problematic reflexivity of modern subjectivity itself, which the discipline of psychology was never able to wholly resolve. From here, I proceed with the argument that while the eagerness of the psy-sciences to embrace neuroscience testifies to how much psychology needs neurology, the neurosciences are structurally incapable of disconnecting from the paradigms of the psy-sciences. Following on from this proposition, other strong/weak factors are brought into the equation: strong/weak nature, strong/weak culture, strong/weak subjectivity and, most pertinently, strong/weak education. Finally, the critical question becomes: if education in itself needs to take recourse to both the psy-sciences and the neurosciences, then how can we begin to account for the fact that these sciences invariably end up becoming captured within educational discourses themselves; that is, the fact that teachers, parents, and pupils themselves are taught the key insights of neuropsychology. (shrink)

Introduction. Eating Disorders (EDs) are serious psychiatric disorders, impacting physical and psychosocial functioning, often with a chronic course and high mortality rates. The two continua model of mental health states that mental health is a complete state, that is not merely the absence of mental illness, but also the presence of mental health. This model was studied among ED patients by comparing the levels of well-being to the Dutch general population and by examining the of well-being and psychopathology. Method. A (...) total of 468 female ED patients participated in this study during application and intake at a specialized ED treatment centre in the Netherlands. They filled out questionnaires about well-being (MHC-SF), general psychopathology (OQ-45), and ED psychopathology (EDE-Q). Categorical and mean well-being levels were calculated. Also, the correlates of these variables were examined with Pearson correlation and multiple hierarchical regression analysis. Results. ED patients showed lower levels of emotional, psychological and social well-being on average compared to the general population. About 26% of the ED patients experienced low levels of well-being (languishing). However, also 13% experienced high levels of well-being (flourishing), varying between 9% in Anorexia Nervosa to 25% in Binge Eating Disorder. ED psychopathology and general well-being showed a moderate negative correlation. For patients with Bulimia Nervosa and Binge Eating Disorder however no such correlation was found. Lower general psychopathology, not having a history of hospitalization for the ED, and adaptive personal functioning were correlated with well-being among ED patients. Conclusion This study shows initial support for the two continua model of mental health among ED patients. Psychopathology and well-being should be considered as related, but distinct dimensions of mental health in ED patients. Further research should focus on the possible reciprocal relationships between psychopathology and well-being during recovery. It is recommended to monitor well-being during treatment and to implement interventions for well-being to realize complete recovery for those patients with inadequate levels of well-being. (shrink)

Recent work in the history of science has questioned the Eurocentric nature of the field and sought to include a more global approach that would serve to displace center–periphery models in favor of approaches that take seriously local knowledge production. Historians of Iberian colonial science have taken up this approach, which involves reliance on indigenous knowledge traditions of the Americas. These traditions present a number of challenges to modern researchers, including availability and reliability of source material, issues of translation and (...) identification, and lack of systematization. This essay explores the challenges that emerged in the author’s attempt to compile a pre-contact Nahua pharmacopeia, the reasons for these challenges, and the ways they may – or may not – be overcome. (shrink)